个人简介
杨捷茹，中南大学湘雅药学院讲师。2015年于英国格林威治大学获生物科学学士学位（一等荣誉），2017年于澳大利亚昆士兰大学获生物技术硕士学位，2022年于昆士兰大学化学与分子生物学院获博士学位，师从Istvan Toth教授和Mariusz Skwarczynski教授。2022-2024年在中南大学从事博士后研究（入选博士后创新人才支持计划），2024年11月起任中南大学湘雅药学院讲师。 主要研究方向包括：利用外泌体工程进行免疫调节与药物递送、纳米药物递送系统开发、经皮给药与免疫治疗以及基因编辑递送系统等。以第一作者在Advanced Science、Journal of Controlled Release、Vaccines等国际期刊发表多篇SCI论文。主持博士后创新人才支持计划（60万元）、湖南省自然科学基金等项目。
研究方向
学术经历
代表性论文（18 篇）
Advances in metal ion-mediated macromolecular drug delivery
Li, K., Yang, J., Peng, Y., Zheng, H., Fu, Z., Li, M., Yu, G.
International Journal of Pharmaceutics(2025)
Hyaluronic Acid-Ornithine Crosslinked Hydrogel as A Superior 3D Culture Platform for High-Quality Exosome Production
Qu S, Zhao R, Li K, Tan Y, Li P, Liu B, Yang J*, Zhou W*
Stem Cell Research & Therapy(2025)
Transdermal Psoriasis Treatment Inspired by Tumor Microenvironment-Mediated Immunomodulation and Advanced by Exosomal Engineering
Jieru Yang, Jiaojiao Zhu, Shan Lu, Hong Qin, Wenhu Zhou*
Journal of Controlled Release(2025)
Mitigating Doxorubicin-Induced Cardiotoxicity and Enhancing Anti-Tumor Efficacy with a Metformin-Integrated Self-Assembled Nanomedicine
Jiaxin Huang, Jieru Yang, Yuanying Yang, Xiaofeng Lu, Juan Xu, Shan Lu, Hong Pan, Wenhu Zhou*, Wenqun Li*, Songwen Chen*
Advanced Science(2025)
The development of surface-modified liposomes as an intranasal delivery system for a peptide-based vaccine against Group A Streptococcus
Yang J, Boer JC, Khongkow M, Phunpee S, Khalil ZG, Bashiri S, Deceneux C, et al.
Harnessing Tumor Cell-Derived Exosomes for Immune Rejection Management in Corneal Transplantation
Jieru Yang, Huanmin Kang, Yingyi Liu, Yan He*, Wenhu Zhou*
Advanced Science(2024)
Repolarizing neutrophils via MnO2 nanoparticle-activated STING pathway enhances Salmonella-mediated tumor immunotherapy
Shan Lu, Ze Mi, Peng Liu, Jinsong Ding, Yiran Ma, Jieru Yang*, Pengfei Rong*, Wenhu Zhou*
Journal of Nanobiotechnology(2024)
Cell-penetrating peptides-based liposomal delivery system for a peptide-based vaccine against Group A Streptococcus
Yang J, Firdaus F, Azuar A, Khalil ZG, Marasini N, Capon RJ, Hussein WM, Toth I, Skwarczynski M.
Liposomal Formulations of a Polyleucine-Antigen Conjugate as Therapeutic Vaccines against Cervical Cancer
Firdaus FZ, Bartlett S, Hussein WM, Lu L, Wright Q, Huang W, Nahar UJ, Yang J, et al.
Pharmaceutics(2023)DOI
Development of a peptide vaccine against hookworm infection: Immunogenicity, efficacy, and immune correlates of protection
Shalash AO, Becker L, Yang J, Giacomin P, Pearson M, Hussein WM, Loukas A, Toth I, Skwarczynski M.
Journal of Allergy and Clinical Immunology(2022)DOI
Oral peptide vaccine against hookworm infection: correlation of antibody titers with protective efficacy
Shalash AO, Becker L, Yang J, Giacomin P, Pearson M, Hussein WM, Loukas A, Skwarczynski M, Toth I.
Vaccines(2021)DOI
Poly (hydrophobic amino acid) Conjugates for the Delivery of Multiepitope Vaccine against Group A Streptococcus
Azuar A, Shibu MA, Adilbish N, Marasini N, Hung H, Yang J, Luo Y, et al.
Bioconjugate Chemistry(2021)DOI
Polyethylenimine quantity and molecular weight influence its adjuvanting properties in liposomal peptide vaccines
Dai CC, Huang W, Yang J, Hussein WM, Wang J, Khalil ZG, Capon RJ, Toth I, Stephenson RJ.
Bioorganic & Medicinal Chemistry Letters(2021)DOI
Polyacrylate-GnRH peptide conjugate as an oral contraceptive vaccine candidate
Faruck MO, Koirala P, Yang J, DOcchio MJ, Skwarczynski M, Toth I.
Pharmaceutics(2021)DOI
A dual-adjuvanting strategy for peptide-based subunit vaccines against group A Streptococcus: Lipidation and polyelectrolyte complexes
Zhao L, Yang J, Nahar UJ, Khalil ZG, Capon RJ, Hussein WM, Skwarczynski M, Toth I.
Bioorganic & Medicinal Chemistry(2020)DOI
Polyethylenimine: An intranasal adjuvant for liposomal peptide-based subunit vaccine against group A Streptococcus
Dai CC, Yang J, Hussein WM, Zhao L, Wang X, Khalil ZG, Capon RJ, Toth I, Stephenson RJ.
ACS Infectious Diseases(2020)DOI
Opsonic activity of conservative versus variable regions of the group A Streptococcus M protein
Dai C, Khalil ZG, Hussein WM, Yang J, Wang X, Zhao L, Capon RJ, Toth I, Stephenson RJ.
Vaccines(2020)DOI
Cell-penetrating peptides: efficient vectors for vaccine delivery
Yang J, Luo Y, Shibu MA, Toth I, Skwarczynski M.
Current Drug Delivery(2019)DOI